Chemeleon develops BINDS™ (Binding-Induced Nanostructured Dynamic Surface), the world's first ultra-rapid, instrument-free assay platform that delivers lab-precision diagnostics to the point of need, empowering immediate action when minutes and missions matter most. BINDS produces a clear, visible color-change result in under one minute from a single drop of sample, with zero sample preparation, no power, and no reader required. The platform works across a wide range of biological and environmental matrices, including whole blood, interstitial fluid, CSF, nasal fluid, saliva, and even water. It can detect proteins, nucleic acids, and small molecules with a limit of detection of 10 ng/L, a 10-log dynamic range, and 97–99% sensitivity / 91–100% specificity. This versatility enables both clinical applications (traumatic brain injury/concussion, CSF leaks, acute myocardial infarction rule-out) and military/dual-use applications (chemical-biological threat detection), all on the same core technology.
$7M
Previous Round
Ultra-rapid cerebrospinal fluid (CSF) leak detection assay delivering lab-precision results in 1-minute turnaround time from raw bio samples with no sample prep. Achieves 97% sensitivity and 100% specificity for detecting CSF leaks in emergency department and surgical settings, eliminating the 4-6 day turnaround time of traditional testing.
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Multiplexed high-sensitivity cardiac troponin and cardiac myosin-binding protein C assay for acute myocardial infarction (AMI) rule-out. Delivers results in under 1 minute at point of care enabling immediate clinical decisions to restore blood flow and prevent cardiac tissue necrosis.
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Multiplexed glial fibrillary acidic protein and ubiquitin C-terminal hydrolase L1 assay for rapid traumatic brain injury (TBI) and concussion detection. Provides objective biomarker-based diagnosis in 1 minute at point of care, addressing the 50% of concussions that currently go undiagnosed due to reliance on subjective clinical evaluations.
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Aptamer-based detection system for chemical and biological threats in battlefield and defense applications. Enables decentralized testing by warfighters with ultra-rapid results, addressing the limitations of current methods that require lab analysis or take hours to confirm threats in field environments.
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